Fear is a dominant player in the markets. Stocks drop, people get scared, and the stock drops more because people are selling...because their scared. Good companies selling at depressed values make excellent opportunities, if you can ignore the fear.
The same applies to stocks increasing in value while you hold a position in it (always a good thing). As the shares increase in value, some people become more and more afraid, especially in these market conditions (April 16, 2009), the questions pass through the mind... is this a true rally, or is this stock about to slide back down, erasing all profits earned.
It is important to ignore fear in both examples. This is accomplished by committing to an entry price and exit price BEFORE taking on a stock position. Before entry, you are thinking clearly, unaffected by the bombardment of emotions as the share value fluctuates. The key to allowing your winners to run is to stay the course and allow the value to raise to the predetermined price...then sell.
A principle I recently acquired and have taken as my own is the 7% rule (found in Jack D. Schwagers' book "Market Wizards"). If you have a working theory about a stock, based on fundamentals and sound reason, take the position, but set a limit order to sell or cover after a 7% loss. This will keep you from losing your shirt on any one trade.